node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C44B12.6 | F25D1.3 | C44B12.6c.1 | F25D1.3.1 | Uncharacterized protein. | Uncharacterized protein. | 0.915 |
C44B12.6 | actl-1 | C44B12.6c.1 | C15B12.6a.1 | Uncharacterized protein. | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.660 |
C44B12.6 | ilcr-1 | C44B12.6c.1 | Y64G10A.6.1 | Uncharacterized protein. | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.853 |
C44B12.6 | ilcr-2 | C44B12.6c.1 | F56D1.2.1 | Uncharacterized protein. | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.852 |
C44B12.6 | kars-1 | C44B12.6c.1 | T02G5.9b.1 | Uncharacterized protein. | Lysine--tRNA ligase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.698 |
C44B12.6 | nfki-1 | C44B12.6c.1 | C33A11.1.1 | Uncharacterized protein. | ANK repeat-containing protein nipk-1; Acts downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. Mediates signaling of the complex; Belongs to the iASPP family. | 0.819 |
C44B12.6 | ops-1 | C44B12.6c.1 | T13A10.13.1 | Uncharacterized protein. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.461 |
F25D1.3 | C44B12.6 | F25D1.3.1 | C44B12.6c.1 | Uncharacterized protein. | Uncharacterized protein. | 0.915 |
F25D1.3 | actl-1 | F25D1.3.1 | C15B12.6a.1 | Uncharacterized protein. | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.660 |
F25D1.3 | ilcr-1 | F25D1.3.1 | Y64G10A.6.1 | Uncharacterized protein. | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.854 |
F25D1.3 | ilcr-2 | F25D1.3.1 | F56D1.2.1 | Uncharacterized protein. | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.853 |
F25D1.3 | nfki-1 | F25D1.3.1 | C33A11.1.1 | Uncharacterized protein. | ANK repeat-containing protein nipk-1; Acts downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. Mediates signaling of the complex; Belongs to the iASPP family. | 0.857 |
F25D1.3 | ops-1 | F25D1.3.1 | T13A10.13.1 | Uncharacterized protein. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.461 |
actl-1 | C44B12.6 | C15B12.6a.1 | C44B12.6c.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Uncharacterized protein. | 0.660 |
actl-1 | F25D1.3 | C15B12.6a.1 | F25D1.3.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Uncharacterized protein. | 0.660 |
actl-1 | ilcr-1 | C15B12.6a.1 | Y64G10A.6.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.942 |
actl-1 | ilcr-2 | C15B12.6a.1 | F56D1.2.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.936 |
actl-1 | nfki-1 | C15B12.6a.1 | C33A11.1.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | ANK repeat-containing protein nipk-1; Acts downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. Mediates signaling of the complex; Belongs to the iASPP family. | 0.908 |
actl-1 | ops-1 | C15B12.6a.1 | T13A10.13.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.741 |
ilcr-1 | C44B12.6 | Y64G10A.6.1 | C44B12.6c.1 | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Uncharacterized protein. | 0.853 |