STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ssb-1Sjogren Syndrome antigen B homolog. (396 aa)    
Predicted Functional Partners:
spsb-1
B30.2/SPRY domain-containing protein.
      
 0.880
F27D4.4
Zinc finger CCCH domain-containing protein 15 homolog; Belongs to the ZC3H15/TMA46 family.
   
    0.764
rop-1
60 kDa SS-A/Ro ribonucleoprotein homolog; RNA-binding protein that binds to a single small cytoplasmic RNA molecule known as Y RNA. May stabilize this RNA from degradation; Belongs to the Ro 60 kDa family.
   
 
 0.762
K07H8.10
RRM domain-containing protein.
   
 
 0.698
snr-4
Probable small nuclear ribonucleoprotein Sm D2; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity).
   
 
 0.681
snr-1
Small nuclear ribonucleoprotein Sm D3; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity); Belongs to the snRNP core protein family.
   
   0.678
cct-8
T-complex protein 1 subunit theta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity). Required for correct subcellular localization of pgl-1; Belongs to the TCP-1 chaperonin family.
   
  
 0.669
ztf-4
RRM domain-containing protein.
   
 
 0.656
hrp-1
Heterogeneous nuclear ribonucleoprotein A1; This protein is a component of ribonucleosomes. Overexpression gradually increases telomere length, leading to increase lifespan.
   
 
 0.655
nol-58
Nop domain-containing protein.
   
   0.643
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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