STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C45B2.6Uncharacterized protein. (762 aa)    
Predicted Functional Partners:
C07E3.9
Phospholipase A(2).
   
  
 0.867
cyp-29A3
CYtochrome P450 family; Belongs to the cytochrome P450 family.
      
 0.850
cyp-33E2
CYtochrome P450 family; Belongs to the cytochrome P450 family.
      
 0.809
rme-2
Receptor Mediated Endocytosis.
      
 0.550
cyp-31A2
CYtochrome P450 family; Belongs to the cytochrome P450 family.
      
 0.531
vps-52
Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function. Belongs to the VPS52 family.
   
  
 0.469
cyp-31A3
CYtochrome P450 family; Belongs to the cytochrome P450 family.
      
 0.461
ipp-5
Probable type I inositol 1,4,5-trisphosphate 5-phosphatase; Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
   
  
 0.423
C01B10.3
Uncharacterized protein.
      
 0.422
acer-1
AcetylCoA_hyd_C domain-containing protein.
      
 0.422
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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