node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aspm-1 | bmk-1 | C45G3.1.1 | F23B12.8b.1 | Calponin-homology (CH) domain-containing protein. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.988 |
aspm-1 | cmd-1 | C45G3.1.1 | T21H3.3a.1 | Calponin-homology (CH) domain-containing protein. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. | 0.958 |
aspm-1 | him-10 | C45G3.1.1 | R12B2.4.1 | Calponin-homology (CH) domain-containing protein. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.962 |
aspm-1 | klp-18 | C45G3.1.1 | C06G3.2.1 | Calponin-homology (CH) domain-containing protein. | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.991 |
aspm-1 | klp-19 | C45G3.1.1 | Y43F4B.6.1 | Calponin-homology (CH) domain-containing protein. | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.953 |
aspm-1 | lin-5 | C45G3.1.1 | T09A5.10.2 | Calponin-homology (CH) domain-containing protein. | Spindle apparatus protein lin-5; Essential component of the spindle apparatus required for spindle positioning and chromosome movement. Acts to recruit or anchor gpr-1/gpr-2 complex to the spindle and cortex. Also involved, directly or indirectly, in cytokinesis and in the coupling of DNA replication, centrosome duplication and mitotic division. | 0.995 |
aspm-1 | ndc-80 | C45G3.1.1 | W01B6.9.1 | Calponin-homology (CH) domain-containing protein. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.929 |
aspm-1 | rod-1 | C45G3.1.1 | F55G1.4.2 | Calponin-homology (CH) domain-containing protein. | Kinetochore-associated protein rod-1; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Plays a role in nuclear envelope breakdown. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome [...] | 0.930 |
aspm-1 | spd-1 | C45G3.1.1 | Y34D9A.4.1 | Calponin-homology (CH) domain-containing protein. | SPD-1. | 0.936 |
aspm-1 | zen-4 | C45G3.1.1 | M03D4.1d.2 | Calponin-homology (CH) domain-containing protein. | Kinesin-like protein. | 0.974 |
bmk-1 | aspm-1 | F23B12.8b.1 | C45G3.1.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Calponin-homology (CH) domain-containing protein. | 0.988 |
bmk-1 | him-10 | F23B12.8b.1 | R12B2.4.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.960 |
bmk-1 | klp-18 | F23B12.8b.1 | C06G3.2.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.961 |
bmk-1 | klp-19 | F23B12.8b.1 | Y43F4B.6.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.861 |
bmk-1 | lin-5 | F23B12.8b.1 | T09A5.10.2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Spindle apparatus protein lin-5; Essential component of the spindle apparatus required for spindle positioning and chromosome movement. Acts to recruit or anchor gpr-1/gpr-2 complex to the spindle and cortex. Also involved, directly or indirectly, in cytokinesis and in the coupling of DNA replication, centrosome duplication and mitotic division. | 0.709 |
bmk-1 | ndc-80 | F23B12.8b.1 | W01B6.9.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.944 |
bmk-1 | rod-1 | F23B12.8b.1 | F55G1.4.2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinetochore-associated protein rod-1; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Plays a role in nuclear envelope breakdown. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome [...] | 0.899 |
bmk-1 | spd-1 | F23B12.8b.1 | Y34D9A.4.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | SPD-1. | 0.991 |
bmk-1 | zen-4 | F23B12.8b.1 | M03D4.1d.2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinesin-like protein. | 0.981 |
cmd-1 | aspm-1 | T21H3.3a.1 | C45G3.1.1 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. | Calponin-homology (CH) domain-containing protein. | 0.958 |