STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srh-100Serpentine Receptor, class H. (347 aa)    
Predicted Functional Partners:
sdf-9
Protein sdf-9; Together with eak-4 and phosphatase eak-6, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1.
   
  
 0.706
clc-1
CLaudin-like in Caenorhabditis.
      
 0.700
F44D12.8
Uncharacterized protein.
      
 0.693
F59B1.2
Uncharacterized protein.
      
 0.693
dct-14
DAF-16/FOXO Controlled, germline Tumor affecting.
      
 0.692
F35E12.9
CUB_2 domain-containing protein.
      
 0.666
hpo-15
Amino_oxidase domain-containing protein.
      
 0.581
F52E1.5
Uncharacterized protein.
      
 0.532
ZK896.5
CUB_2 domain-containing protein.
      
 0.465
srb-3
Serpentine receptor class beta-3; G-protein coupled receptor.
   
    0.457
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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