STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C47G2.4G-protein coupled receptor-associated protein LMBRD2; May associate with G-protein coupled receptors and regulate downstream signaling pathways; Belongs to the LIMR family. (644 aa)    
Predicted Functional Partners:
C47G2.3
Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
 
 
    0.812
F58B3.4
NUC153 domain-containing protein.
   
  
 0.560
F17A9.2
CWF19-like protein 1 homolog; Belongs to the CWF19 family.
   
    0.538
apg-1
AP-1 complex subunit gamma.
   
  
 0.494
lex-1
Tat-binding homolog 7; Thought to form a complex that enhances transcription from repetitive DNA sequences by modulating chromatin structure. Belongs to the AAA ATPase family.
   
  
 0.473
mex-3
Muscle EXcess.
   
  
 0.466
hum-2
Dilute domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.440
rpl-24.2
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity).
      
 0.402
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.