node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F33D11.10 | erfa-1 | F33D11.10.1 | T05H4.6a.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | 0.468 |
F33D11.10 | smg-1 | F33D11.10.1 | C48B6.6a.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.970 |
F33D11.10 | smg-2 | F33D11.10.1 | Y48G8AL.6.2 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an smg-2-3-4 surveillance complex is believed to activate NMD (By similarity). | 0.900 |
F33D11.10 | smg-3 | F33D11.10.1 | Y73B6BL.18b.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Suppressor with Morphological effect on Genitalia. | 0.830 |
F33D11.10 | smg-4 | F33D11.10.1 | F46B6.3b.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Smg4_UPF3 domain-containing protein. | 0.967 |
F33D11.10 | smg-5 | F33D11.10.1 | W02D3.8.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Nonsense-mediated mRNA decay protein. | 0.839 |
F33D11.10 | smg-6 | F33D11.10.1 | Y54F10AL.2a.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | PINc domain-containing protein. | 0.790 |
F33D11.10 | smg-8 | F33D11.10.1 | K04B12.3a.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Protein smg-8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG8 family. | 0.764 |
F33D11.10 | smg-9 | F33D11.10.1 | Y54E2A.2.1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Protein smg-9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG9 family. | 0.742 |
daf-15 | smg-1 | C10C5.6c.1 | C48B6.6a.1 | Raptor_N domain-containing protein. | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.968 |
erfa-1 | F33D11.10 | T05H4.6a.1 | F33D11.10.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Uncharacterized protein; Belongs to the DEAD box helicase family. | 0.468 |
erfa-1 | smg-1 | T05H4.6a.1 | C48B6.6a.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.980 |
erfa-1 | smg-2 | T05H4.6a.1 | Y48G8AL.6.2 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an smg-2-3-4 surveillance complex is believed to activate NMD (By similarity). | 0.920 |
erfa-1 | smg-3 | T05H4.6a.1 | Y73B6BL.18b.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Suppressor with Morphological effect on Genitalia. | 0.760 |
erfa-1 | smg-4 | T05H4.6a.1 | F46B6.3b.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Smg4_UPF3 domain-containing protein. | 0.763 |
erfa-1 | smg-5 | T05H4.6a.1 | W02D3.8.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Nonsense-mediated mRNA decay protein. | 0.749 |
erfa-1 | smg-6 | T05H4.6a.1 | Y54F10AL.2a.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | PINc domain-containing protein. | 0.855 |
erfa-1 | smg-8 | T05H4.6a.1 | K04B12.3a.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Protein smg-8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG8 family. | 0.914 |
erfa-1 | smg-9 | T05H4.6a.1 | Y54E2A.2.1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. | Protein smg-9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG9 family. | 0.939 |
smg-1 | F33D11.10 | C48B6.6a.1 | F33D11.10.1 | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | Uncharacterized protein; Belongs to the DEAD box helicase family. | 0.970 |