Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| akt-1 | akt-2 | C12D8.10b.2 | F28H6.1a.1 | Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] | Serine/threonine-protein kinase akt-2; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating developmental arrest at the dauer stage. Phosphorylates Forkhead-related daf- 16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Role in immune function and pathogen resistance. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic development. Belongs to the protein kinase superfamily. [...] | 0.956 |
| akt-1 | nhr-6 | C12D8.10b.2 | C48D5.1a.1 | Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.765 |
| akt-2 | akt-1 | F28H6.1a.1 | C12D8.10b.2 | Serine/threonine-protein kinase akt-2; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating developmental arrest at the dauer stage. Phosphorylates Forkhead-related daf- 16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Role in immune function and pathogen resistance. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic development. Belongs to the protein kinase superfamily. [...] | Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] | 0.956 |
| akt-2 | nhr-6 | F28H6.1a.1 | C48D5.1a.1 | Serine/threonine-protein kinase akt-2; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating developmental arrest at the dauer stage. Phosphorylates Forkhead-related daf- 16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Role in immune function and pathogen resistance. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic development. Belongs to the protein kinase superfamily. [...] | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.769 |
| blmp-1 | fos-1 | F25D7.3a.1 | F29G9.4b.1 | B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...] | Transcription factor fos-1; Developmentally regulated transcription factor which binds and recognizes the enhancer DNA sequence 5'-TGA[CG]TCA-3'. [Isoform b]: Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. Acts with hda-1 as a downstream repressor of the kgb-1 mediated stress response pathway that transcriptionally represses genes involved in the response to heavy metals, such as kreg-1 ; Belongs to the bZIP family. Fos subfamily. | 0.426 |
| blmp-1 | nhr-6 | F25D7.3a.1 | C48D5.1a.1 | B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...] | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.721 |
| ceh-14 | nhr-6 | F46C8.5.1 | C48D5.1a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.517 |
| cgef-1 | nhr-6 | C14A11.3b.1 | C48D5.1a.1 | DH domain-containing protein. | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.531 |
| cgef-1 | pix-1 | C14A11.3b.1 | K11E4.4a.1 | DH domain-containing protein. | PIX (PAK (p21-activated kinase) Interacting eXchange factor) homolog. | 0.691 |
| fos-1 | blmp-1 | F29G9.4b.1 | F25D7.3a.1 | Transcription factor fos-1; Developmentally regulated transcription factor which binds and recognizes the enhancer DNA sequence 5'-TGA[CG]TCA-3'. [Isoform b]: Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. Acts with hda-1 as a downstream repressor of the kgb-1 mediated stress response pathway that transcriptionally represses genes involved in the response to heavy metals, such as kreg-1 ; Belongs to the bZIP family. Fos subfamily. | B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...] | 0.426 |
| fos-1 | jun-1 | F29G9.4b.1 | T24H10.7a.1 | Transcription factor fos-1; Developmentally regulated transcription factor which binds and recognizes the enhancer DNA sequence 5'-TGA[CG]TCA-3'. [Isoform b]: Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. Acts with hda-1 as a downstream repressor of the kgb-1 mediated stress response pathway that transcriptionally represses genes involved in the response to heavy metals, such as kreg-1 ; Belongs to the bZIP family. Fos subfamily. | Transcription factor jun-1; Transcription factor that recognizes and binds to the AP-1 non-canonical enhancer heptamer motif 5'-TTAGTCA-3'. Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. | 0.990 |
| fos-1 | nhr-6 | F29G9.4b.1 | C48D5.1a.1 | Transcription factor fos-1; Developmentally regulated transcription factor which binds and recognizes the enhancer DNA sequence 5'-TGA[CG]TCA-3'. [Isoform b]: Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. Acts with hda-1 as a downstream repressor of the kgb-1 mediated stress response pathway that transcriptionally represses genes involved in the response to heavy metals, such as kreg-1 ; Belongs to the bZIP family. Fos subfamily. | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.499 |
| gei-8 | nhr-6 | C14B9.6a.3 | C48D5.1a.1 | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Plays a role in development and neuronal function. May play a role in muscle-specific oxidative mitochondrial metabolism. | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.618 |
| jun-1 | fos-1 | T24H10.7a.1 | F29G9.4b.1 | Transcription factor jun-1; Transcription factor that recognizes and binds to the AP-1 non-canonical enhancer heptamer motif 5'-TTAGTCA-3'. Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. | Transcription factor fos-1; Developmentally regulated transcription factor which binds and recognizes the enhancer DNA sequence 5'-TGA[CG]TCA-3'. [Isoform b]: Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. Acts with hda-1 as a downstream repressor of the kgb-1 mediated stress response pathway that transcriptionally represses genes involved in the response to heavy metals, such as kreg-1 ; Belongs to the bZIP family. Fos subfamily. | 0.990 |
| jun-1 | nhr-6 | T24H10.7a.1 | C48D5.1a.1 | Transcription factor jun-1; Transcription factor that recognizes and binds to the AP-1 non-canonical enhancer heptamer motif 5'-TTAGTCA-3'. Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation. | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | 0.664 |
| nhr-6 | akt-1 | C48D5.1a.1 | C12D8.10b.2 | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] | 0.765 |
| nhr-6 | akt-2 | C48D5.1a.1 | F28H6.1a.1 | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | Serine/threonine-protein kinase akt-2; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating developmental arrest at the dauer stage. Phosphorylates Forkhead-related daf- 16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Role in immune function and pathogen resistance. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic development. Belongs to the protein kinase superfamily. [...] | 0.769 |
| nhr-6 | blmp-1 | C48D5.1a.1 | F25D7.3a.1 | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...] | 0.721 |
| nhr-6 | ceh-14 | C48D5.1a.1 | F46C8.5.1 | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.517 |
| nhr-6 | cgef-1 | C48D5.1a.1 | C14A11.3b.1 | Nuclear hormone receptor family member nhr-6; Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which [...] | DH domain-containing protein. | 0.531 |
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