STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tkr-2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)    
Predicted Functional Partners:
egl-30
Heterotrimeric G protein alpha subunit.
    
 0.910
old-2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
      
 0.808
T24C4.5
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.660
pvf-1
PDGF_2 domain-containing protein.
      
 0.543
seb-3
Secretin receptor-like protein SEB-3; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.540
ver-1
Protein ver-1; Involved in amphid glia remodeling during entry into dauer stage by promoting the fusion of sheath amphid cells which encloses AWC neuron sensory endings. May be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.
      
 0.501
F25H9.7
Uncharacterized protein.
    
 
 0.493
lgc-36
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.481
F09A5.2
Putative tyrosine-protein kinase F09A5.2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
      
 0.463
skr-8
SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family.
      
 0.429
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.