STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gem-1Gon-2 Extragenic Modifier. (771 aa)    
Predicted Functional Partners:
catp-7
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
   
  
 0.818
gon-2
Transient receptor potential channel; Required for initiation and continuation of postembryonic mitotic cell divisions of gonadal cells Z1 and Z4. Zygotic expression is necessary for hermaphrodite fertility. May be a cation channel. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily.
   
  
 0.813
miro-1
Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
    
 
 0.766
gtl-1
LSDAT_euk domain-containing protein.
   
  
 0.716
catp-5
Cation-transporting ATPase catp-5; Involved in the uptake and/or transport of polyamines, probably through ATP hydrolysis. This contributes to the maintenance of intracellular polyamine levels. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
   
  
 0.710
gem-4
Gon-2 Extragenic Modifier.
      
 0.698
catp-6
Probable cation-transporting ATPase W08D2.5; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
   
  
 0.695
T13H5.6
Uncharacterized protein.
      
 0.694
imp-2
Intramembrane protease 2; Acts as intramembrane protease (Probable). In larvae, required for the complete shedding of the cuticle during molting, possibly by regulating cholesterol uptake via lrp-1. Involved in embryonic and larval development ; Belongs to the peptidase A22B family.
      
 0.682
catp-1
Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
   
 
 0.676
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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