STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntl-4NOT-Like (Yeast CCR4/NOT complex component). (798 aa)    
Predicted Functional Partners:
ntl-9
NOT-Like (Yeast CCR4/NOT complex component).
   
 0.990
ccf-1
CCR4-NOT transcription complex subunit 7; Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression; Belongs to the CAF1 family.
   
 0.990
let-711
Not1 domain-containing protein.
   
 0.982
ntl-3
NOT2_3_5 domain-containing protein.
   
 0.978
ntl-2
NOT2_3_5 domain-containing protein.
   
 0.975
cgh-1
ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
   
 
 0.965
tag-153
NOT2_3_5 domain-containing protein.
   
 0.959
ccr-4
Endo/exonuclease/phosphatase domain-containing protein.
   
 0.957
mtr-4
mRNA transport homolog 4.
   
 
 0.934
rbm-42
RRM domain-containing protein.
      
 0.928
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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