STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
str-193Seven TM Receptor. (347 aa)    
Predicted Functional Partners:
gpa-6
Guanine nucleotide-binding protein alpha-6 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family.
      
 0.698
gsa-1
G protein, Subunit Alpha.
      
 0.531
ocr-2
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.461
daf-11
Receptor-type guanylate cyclase daf-11; Guanylate cyclase involved in the production of the second messenger cGMP. In addition, regulates cGMP levels by controlling the transcription of 3',5'-cyclic phosphodiesterase pde-1 and pde-5 mRNAs. Involved in the olfactory, light and pheromone sensing pathways. Part of the chemosensory mechanism of the ASJ sensory neuron that controls dauer formation and dauer recovery. Promotes the calcium flux in ASJ sensory neurons in response to onset and removal of a nitric oxide (NO) stimulus and is thereby required for the behavioral avoidance response [...]
   
  
 0.428
str-7
Seven TM Receptor.
      
0.410
srv-22
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
    0.407
srd-66
Serpentine Receptor, class D (Delta).
   
    0.405
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.