STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C50D2.3PDZ domain-containing protein. (152 aa)    
Predicted Functional Partners:
ZK1248.5
DUF1248 domain-containing protein.
   
    0.615
nkb-2
Na+/K+ ATPase, Beta subunit.
   
    0.592
F13A7.1
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
   0.592
K05F1.9
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
    0.592
cyc-2.2
Probable cytochrome c 2.2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
   
    0.592
spe-11
Spermatocyte protein spe-11; Paternally sperm-supplied factor required for embryogenesis. Plays a role in preventing polyspermy possibly by promoting the formation of a continuous and cohesive eggshell chitin layer.
   
    0.583
C08F11.10
Uncharacterized protein.
   
    0.581
Y105C5B.18
Uncharacterized protein.
   
    0.581
F32B6.4
Uncharacterized protein.
   
    0.579
C14A6.13
Uncharacterized protein.
   
    0.578
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.