node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C50E3.5 | eif-2Bdelta | C50E3.5.1 | F11A3.2a.1 | Uncharacterized protein. | Eukaryotic Initiation Factor; Belongs to the eIF-2B alpha/beta/delta subunits family. | 0.404 |
C50E3.5 | nhx-2 | C50E3.5.1 | B0495.4.1 | Uncharacterized protein. | Na(+)/H(+) exchanger protein 2; Na(+)/H(+) antiporter that promotes normal di- or tripeptide transporter function, recovery following the peptide-induced acidification of the intestinal cytoplasm and maintenance of the peptide-dependent intestinal pH homeostasis. Regulator of free fatty acid uptake from the diet together with the dipeptide transporter pept- 1. May play a timekeeper role in defecation cycle but is not necessary for pbo-4-dependent proton release. May play a role in the regulation of lifespan independent of the stress response pathway. | 0.544 |
C50E3.5 | nlp-16 | C50E3.5.1 | T13A10.5a.1 | Uncharacterized protein. | Neuropeptide-Like Protein. | 0.665 |
C50E3.5 | nmt-1 | C50E3.5.1 | T17E9.2b.1 | Uncharacterized protein. | Probable glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. | 0.703 |
C50E3.5 | rsp-1 | C50E3.5.1 | W02B12.3a.1 | Uncharacterized protein. | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | 0.816 |
C50E3.5 | scc-1 | C50E3.5.1 | F10G7.4.1 | Uncharacterized protein. | Sister chromatid cohesion protein 1; Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At metaphase-anaphase transition, this protein is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity). | 0.748 |
C50E3.5 | syx-5 | C50E3.5.1 | F55A11.2.1 | Uncharacterized protein. | Putative syntaxin-5; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.667 |
C50E3.5 | unc-89 | C50E3.5.1 | C09D1.1b.1 | Uncharacterized protein. | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | 0.490 |
C50E3.5 | wdr-5.1 | C50E3.5.1 | C14B1.4.2 | Uncharacterized protein. | WD repeat-containing protein wdr-5.1; Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. Required for di- and trimethylation, particularly for the trimethylation at 'Lys-4' of histone H3. Not required for demethylation of histone H3 'Lys-27'. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, germline establishment, maintenance and function. Implicated in the epigenetic inheritance of lifespan over several generations. Acts in the germline to limit the longevity of the soma, pr [...] | 0.583 |
eif-2Bdelta | C50E3.5 | F11A3.2a.1 | C50E3.5.1 | Eukaryotic Initiation Factor; Belongs to the eIF-2B alpha/beta/delta subunits family. | Uncharacterized protein. | 0.404 |
nhx-2 | C50E3.5 | B0495.4.1 | C50E3.5.1 | Na(+)/H(+) exchanger protein 2; Na(+)/H(+) antiporter that promotes normal di- or tripeptide transporter function, recovery following the peptide-induced acidification of the intestinal cytoplasm and maintenance of the peptide-dependent intestinal pH homeostasis. Regulator of free fatty acid uptake from the diet together with the dipeptide transporter pept- 1. May play a timekeeper role in defecation cycle but is not necessary for pbo-4-dependent proton release. May play a role in the regulation of lifespan independent of the stress response pathway. | Uncharacterized protein. | 0.544 |
nlp-16 | C50E3.5 | T13A10.5a.1 | C50E3.5.1 | Neuropeptide-Like Protein. | Uncharacterized protein. | 0.665 |
nmt-1 | C50E3.5 | T17E9.2b.1 | C50E3.5.1 | Probable glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. | Uncharacterized protein. | 0.703 |
nmt-1 | rsp-1 | T17E9.2b.1 | W02B12.3a.1 | Probable glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | 0.471 |
rsp-1 | C50E3.5 | W02B12.3a.1 | C50E3.5.1 | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | Uncharacterized protein. | 0.816 |
rsp-1 | nmt-1 | W02B12.3a.1 | T17E9.2b.1 | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | Probable glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. | 0.471 |
rsp-1 | scc-1 | W02B12.3a.1 | F10G7.4.1 | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | Sister chromatid cohesion protein 1; Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At metaphase-anaphase transition, this protein is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity). | 0.476 |
rsp-1 | wdr-5.1 | W02B12.3a.1 | C14B1.4.2 | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | WD repeat-containing protein wdr-5.1; Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. Required for di- and trimethylation, particularly for the trimethylation at 'Lys-4' of histone H3. Not required for demethylation of histone H3 'Lys-27'. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, germline establishment, maintenance and function. Implicated in the epigenetic inheritance of lifespan over several generations. Acts in the germline to limit the longevity of the soma, pr [...] | 0.428 |
scc-1 | C50E3.5 | F10G7.4.1 | C50E3.5.1 | Sister chromatid cohesion protein 1; Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At metaphase-anaphase transition, this protein is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity). | Uncharacterized protein. | 0.748 |
scc-1 | rsp-1 | F10G7.4.1 | W02B12.3a.1 | Sister chromatid cohesion protein 1; Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At metaphase-anaphase transition, this protein is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity). | Probable splicing factor, arginine/serine-rich 1; Plays a functionally redundant role in spermatogenesis and growth rate control. | 0.476 |