node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F13E6.2 | F38B6.4 | F13E6.2.1 | F38B6.4.1 | Uncharacterized protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.702 |
F13E6.2 | T19B4.3 | F13E6.2.1 | T19B4.3.1 | Uncharacterized protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.675 |
F13E6.2 | lin-2 | F13E6.2.1 | F17E5.1a.1 | Uncharacterized protein. | Protein lin-2; May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions. | 0.613 |
F13E6.2 | magu-3 | F13E6.2.1 | C50F2.8.1 | Uncharacterized protein. | Guanylate kinase-like domain-containing protein. | 0.603 |
F38B6.4 | F13E6.2 | F38B6.4.1 | F13E6.2.1 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Uncharacterized protein. | 0.702 |
F38B6.4 | T19B4.3 | F38B6.4.1 | T19B4.3.1 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.922 |
F38B6.4 | gmps-1 | F38B6.4.1 | M106.4b.1 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Probable GMP synthase [glutamine-hydrolyzing]. | 0.936 |
F38B6.4 | let-754 | F38B6.4.1 | C29E4.8.2 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. | 0.703 |
F38B6.4 | lin-2 | F38B6.4.1 | F17E5.1a.1 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Protein lin-2; May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions. | 0.757 |
F38B6.4 | magu-3 | F38B6.4.1 | C50F2.8.1 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Guanylate kinase-like domain-containing protein. | 0.757 |
T19B4.3 | F13E6.2 | T19B4.3.1 | F13E6.2.1 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Uncharacterized protein. | 0.675 |
T19B4.3 | F38B6.4 | T19B4.3.1 | F38B6.4.1 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.922 |
T19B4.3 | gmps-1 | T19B4.3.1 | M106.4b.1 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Probable GMP synthase [glutamine-hydrolyzing]. | 0.994 |
T19B4.3 | let-754 | T19B4.3.1 | C29E4.8.2 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. | 0.977 |
T19B4.3 | lin-2 | T19B4.3.1 | F17E5.1a.1 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Protein lin-2; May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions. | 0.729 |
T19B4.3 | magu-3 | T19B4.3.1 | C50F2.8.1 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase-like domain-containing protein. | 0.717 |
afd-1 | lin-2 | W03F11.6c.1 | F17E5.1a.1 | PDZ domain-containing protein. | Protein lin-2; May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions. | 0.505 |
afd-1 | magu-3 | W03F11.6c.1 | C50F2.8.1 | PDZ domain-containing protein. | Guanylate kinase-like domain-containing protein. | 0.683 |
eat-20 | let-413 | H30A04.1b.1 | F26D11.11b.1 | Abnormal pharyngeal pumping eat-20; Regulates pharyngeal pumping during feeding. | Protein lap1; Critical role in assembling adherens junctions; adapter protein involved in polarizing protein trafficking in epithelial cells. Necessary to maintain, not establish, the entire terminal web (organelle-depleted, intermediate filament-rich layer of cytoplasm that underlies the apical microvilli of polarized epithelial cells) or brush border assembly at the apical surface gut cells. Required for correct localization of ifb-2 intermediate filaments in the terminal web. Required for dlg-1 lateral localization. With dlg-1, cooperatively regulates ajm-1 localization to apical ju [...] | 0.783 |
eat-20 | magu-3 | H30A04.1b.1 | C50F2.8.1 | Abnormal pharyngeal pumping eat-20; Regulates pharyngeal pumping during feeding. | Guanylate kinase-like domain-containing protein. | 0.595 |