STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfk-1.2ATP-dependent 6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (756 aa)    
Predicted Functional Partners:
gpi-1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.998
tkt-1
Transket_pyr domain-containing protein.
  
 
 0.995
aldo-1
Fructose-bisphosphate aldolase 1.
  
 0.994
fbp-1
FBPase domain-containing protein; Belongs to the FBPase class 1 family.
    
 0.992
tald-1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.988
aldo-2
Fructose-bisphosphate aldolase 2.
  
 0.986
enol-1
Enolase; Belongs to the enolase family.
  
 
 0.981
hxk-1
Phosphotransferase; Belongs to the hexokinase family.
   
 
 0.967
pyk-1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.964
pgk-1
Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.954
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.