STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C50F7.5Uncharacterized protein. (306 aa)    
Predicted Functional Partners:
C42D4.1
DUF148 domain-containing protein.
   
 
 0.754
clx-1
CoLlagen sequence X-hybridizing.
   
 
 0.740
C08E8.3
Uncharacterized protein.
   
  
 0.705
fbxa-59
F-box domain-containing protein.
   
  
 0.703
F15E6.4
Uncharacterized protein.
      
 0.698
C49C8.5
Fibrinogen C-terminal domain-containing protein.
   
 
 0.647
hecw-1
E3 ubiquitin-protein ligase hecw-1; E3 ubiquitin-protein ligase (By similarity). Functions in the OLL neurons in the anterior ganglion to inhibit avoidance to microbial pathogens such as P.aeruginosa although worms do display avoidance behavior, vacating a P.aeruginosa lawn within 24 hours. Likely to act by inhibiting the neuropeptide receptor npr-1.
    
 
 0.610
fbxa-165
F-box domain-containing protein.
   
  
 0.555
ugt-44
UDP-GlucuronosylTransferase.
   
  
 0.544
C23H4.6
AAA_23 domain-containing protein.
   
 
 0.498
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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