STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C52A10.2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (544 aa)    
Predicted Functional Partners:
ges-1
Gut esterase 1; Belongs to the type-B carboxylesterase/lipase family.
  
 
 
0.916
F13H6.3
Esterase CM06B1; Belongs to the type-B carboxylesterase/lipase family.
  
 
 
0.908
Y105E8B.9
Uncharacterized protein.
   
 0.904
cdd-1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
  0.900
cdd-2
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
     
  0.900
C44B7.12
Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A); Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
  
  
 0.862
hint-1
Histidine triad nucleotide-binding protein 1.
   
  
 0.758
ugt-55
Putative UDP-glucuronosyltransferase ugt-55; Belongs to the UDP-glycosyltransferase family.
     
 0.713
set-28
SET domain-containing protein.
      
 0.666
dhs-9
DeHydrogenases, Short chain.
   
  
 0.665
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.