STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ets-9ETS domain-containing protein. (396 aa)    
Predicted Functional Partners:
unc-120
MADS-box domain-containing protein.
    
 
 0.865
elf-1
ETS domain-containing protein.
    
 
 0.843
nhr-119
Nuclear Hormone Receptor family.
    
 
 0.811
F19F10.1
ETS domain-containing protein.
      
 0.806
nhr-265
Nuclear Hormone Receptor family.
    
 
 0.747
ets-7
ETS domain-containing protein.
      
 0.741
ets-8
ETS domain-containing protein.
      
 0.699
ceh-23
Homeobox protein ceh-23.
      
 0.660
nhr-77
Nuclear hormone receptor family member nhr-77; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
    
 
 0.552
ets-4
Transcription factor ets-4; Transcription factor which binds to 5'-GGAA/T-3' DNA consensus sequences. Both positively and negatively regulates the expression of target genes. Plays a role in the regulation of adult lifespan, which may in part be through modulation of daf-16 activity. Regulates the expression of genes such as svh-2 in response to axon injury and in addition, may function downstream of the cAMP signaling pathway to promote axon regeneration. Regulates the expression of lipid metabolism genes and may also control the expression of the RNA-binding protein rege-1 which too [...]
   
 
 0.526
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.