STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lst-6Lateral Signaling Target. (1487 aa)    
Predicted Functional Partners:
sqv-7
UDP-sugar transporter sqv-7; Involved in the import of UDP-glucuronic acid (UDP-GlcA), UDP-N-acetylgalactosamine (UDP-GalNAc) and UDP-galactose (UDP-Gal) from the cytoplasm into the Golgi lumen for the biosynthesis of glycoconjugates that play a pivotal role in development. Involved in the synthesis of chondroitin sulfate and heparan sulfate proteoglycans. Required for embryonic development. Involved in vulva epithelium invagination and embryonic development. Involved in the directed migration of hermaphrodite-specific neurons. Belongs to the TPT transporter family. SLC35D subfamily.
 
 
    0.898
mrpl-2
Ribosomal_L2_C domain-containing protein.
   
 
 0.697
mask-1
Ankyrin repeat and KH domain-containing protein mask-1; Belongs to the mask family.
   
    0.600
haf-2
HAlF transporter (PGP related).
   
    0.596
ten-1
Teneurin-1; Plays a role in the gonadal basement membrane maintenance and/or adhesion early in development. Contributes to the guidance of pharyngeal neurons.
   
  
 0.580
F23H11.2
TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity).
   
    0.574
ZK792.5
Uncharacterized protein.
   
  
 0.569
cogc-3
Conserved Oligomeric Golgi (COG) Component.
   
  
 0.566
rpl-21
60S ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family.
   
   0.560
isw-1
Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
   
    0.559
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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