STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mif-2MIF-like protein mif-2; Belongs to the MIF family. (141 aa)    
Predicted Functional Partners:
T28F4.5
Uncharacterized protein.
   
  
 0.903
mif-4
MIF (Macrophage migration Inhibitory Factor) related.
      
 0.894
col-170
Col_cuticle_N domain-containing protein.
      
 0.852
nas-15
Zinc metalloproteinase nas-15; Metalloprotease.
      
 0.760
nas-13
Zinc metalloproteinase nas-13; Metalloprotease.
      
 0.741
R102.1
DUF4440 domain-containing protein.
      
 0.694
bir-1
Chromosomal passenger complex protein bir-1; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis. The CPC complex has essential functions at the centromere in ensuring correct chromosome condensation, alignment and segregation. In the complex, required to direct the Aurora B/air-2 kinase to chromosomes. Also functions in spindle midzone formation and in the formation of polar bodies during oogenesis. Required for the localization of the kinetochore component hcp-1 to chromosomes. Involved in the positive [...]
   
 
 0.688
F43G9.4
Uncharacterized protein.
      
 0.660
rla-1
60S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
   
  
 0.628
mif-1
MIF (Macrophage migration Inhibitory Factor) related.
  
  
0.591
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.