STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mans-2Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity). (590 aa)    
Predicted Functional Partners:
mans-3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
 
0.954
mans-4
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
  
0.945
gly-12
UDP-N-acetylglucosamine:a-3-D-mannoside b-1,2-N-acetylglucosaminyltransferase I.
   
 0.929
gly-13
Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans (By similarity); Belongs to the glycosyltransferase 13 family.
   
 0.924
gly-14
UDP-N-acetylglucosamine:a-3-D-mannoside b-1,2-N-acetylglucosaminyltransferase I.
    
 0.923
mans-1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
 
0.914
dhs-3
Protein dhs-3; May play a role in lipid droplet formation. May modulate triglyceride levels; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.667
aman-2
Alpha-mann_mid domain-containing protein.
   
  
 0.512
vit-6
Vitellogenin-6; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Probable). May play a role in cholesterol uptake. May be involved in thermotolerance.
      
 0.463
R11F4.1
Probable glycerol kinase; Belongs to the FGGY kinase family.
 
 
    0.421
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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