STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C53A5.2Uncharacterized protein. (86 aa)    
Predicted Functional Partners:
ril-1
RNAi-Induced Longevity.
      
 0.804
ntl-9
NOT-Like (Yeast CCR4/NOT complex component).
    
   0.713
nrd-1
NRD (Yeast Nuclear pre-mRNA Down-regulation) homolog.
    
 
 0.713
crn-3
HRDC domain-containing protein.
   
 
 0.691
F07E5.5
Uncharacterized protein.
   
 
 0.632
K08D12.3
CCHC-type domain-containing protein.
   
 
 0.632
ZK1067.2
NFX1-type zinc finger-containing protein 1 homolog; Epigenetic inheritance factor which, in association with the Argonaute protein wago-4, mediates small RNA-directed transgenerational epigenetic inheritance and thus balances the transgenerational inheritance of epigenetic information. Specifically, maintains a balanced production of small RNAs by preventing the spread of epigenetic signals towards the 5'-end of target mRNAs. Plays a role in small RNA- induced gene silencing in the germline.
    
 
 0.500
skih-2
SKI (Yeast SuperKIller) Helicase homolog.
   
 
 0.477
C28H8.3
Uncharacterized helicase C28H8.3.
   
 
 0.474
mtr-4
mRNA transport homolog 4.
   
 
 0.474
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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