node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aex-2 | clik-1 | T14B1.2.1 | T25F10.6a.2 | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | CaLponIn-liKe proteins. | 0.694 |
aex-2 | clik-2 | T14B1.2.1 | C53C9.2.2 | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | Uncharacterized protein C53C9.2; Belongs to the calponin family. | 0.798 |
aex-2 | clik-3 | T14B1.2.1 | K03E5.2a.1 | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | CaLponIn-liKe proteins. | 0.660 |
aex-2 | ubc-17 | T14B1.2.1 | B0403.2.2 | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | Probable ubiquitin-conjugating enzyme protein 17; Belongs to the ubiquitin-conjugating enzyme family. | 0.476 |
clik-1 | aex-2 | T25F10.6a.2 | T14B1.2.1 | CaLponIn-liKe proteins. | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | 0.694 |
clik-1 | clik-2 | T25F10.6a.2 | C53C9.2.2 | CaLponIn-liKe proteins. | Uncharacterized protein C53C9.2; Belongs to the calponin family. | 0.467 |
clik-1 | cpn-4 | T25F10.6a.2 | F49D11.8.1 | CaLponIn-liKe proteins. | Calponin-homology (CH) domain-containing protein. | 0.640 |
clik-1 | ifa-1 | T25F10.6a.2 | F38B2.1d.1 | CaLponIn-liKe proteins. | Intermediate filament protein ifa-1; Cytoplasmic intermediate filaments make up the structural component of the cytoskeleton providing mechanical strength to cells. Essential protein required during embryogenesis especially for survival past the L1 larva stage, involved in intestine morphogenesis. | 0.400 |
clik-2 | aex-2 | C53C9.2.2 | T14B1.2.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | 0.798 |
clik-2 | clik-1 | C53C9.2.2 | T25F10.6a.2 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | CaLponIn-liKe proteins. | 0.467 |
clik-2 | clik-3 | C53C9.2.2 | K03E5.2a.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | CaLponIn-liKe proteins. | 0.424 |
clik-2 | cpn-4 | C53C9.2.2 | F49D11.8.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | Calponin-homology (CH) domain-containing protein. | 0.414 |
clik-2 | ifa-1 | C53C9.2.2 | F38B2.1d.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | Intermediate filament protein ifa-1; Cytoplasmic intermediate filaments make up the structural component of the cytoskeleton providing mechanical strength to cells. Essential protein required during embryogenesis especially for survival past the L1 larva stage, involved in intestine morphogenesis. | 0.430 |
clik-2 | myo-1 | C53C9.2.2 | R06C7.10.2 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | Myosin-1; Muscle contraction. | 0.549 |
clik-2 | myo-2 | C53C9.2.2 | T18D3.4.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | Myosin-2; Muscle contraction. | 0.570 |
clik-2 | pqn-94 | C53C9.2.2 | ZC15.8.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | Prion-like-(Q/N-rich)-domain-bearing protein. | 0.448 |
clik-2 | tnt-4 | C53C9.2.2 | T08B1.2c.1 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | TropoNin T. | 0.592 |
clik-2 | ubc-17 | C53C9.2.2 | B0403.2.2 | Uncharacterized protein C53C9.2; Belongs to the calponin family. | Probable ubiquitin-conjugating enzyme protein 17; Belongs to the ubiquitin-conjugating enzyme family. | 0.463 |
clik-3 | aex-2 | K03E5.2a.1 | T14B1.2.1 | CaLponIn-liKe proteins. | G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine. | 0.660 |
clik-3 | clik-2 | K03E5.2a.1 | C53C9.2.2 | CaLponIn-liKe proteins. | Uncharacterized protein C53C9.2; Belongs to the calponin family. | 0.424 |