STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhx-3Probable Na(+)/H(+) antiporter nhx-3; Plays a role in epithelial membrane transport processes. (670 aa)    
Predicted Functional Partners:
rhr-2
Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
 
 0.974
rhr-1
Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
 
 0.974
F13B12.4
Putative pyridoxal-phosphate dependent protein F13B12.4; Belongs to the cysteine synthase/cystathionine beta- synthase family. Highly divergent.
     
 0.892
F28H1.1
Uncharacterized protein.
      
 0.892
T01D3.6
Uncharacterized protein.
   
  
 0.829
fil-2
Fasting Induced Lipase.
      
 0.805
lpr-4
LiPocalin-Related protein.
  
  
 0.753
cpt-4
Carn_acyltransf domain-containing protein.
   
  
 0.705
zig-4
Zwei Ig domain protein zig-4; Required for maintaining axon position of PVQ and PVP neurons postembryonically in the ventral nerve cord (VNC) by preventing axons drifting into the opposite side of the VNC that could occur during body growth and movement.
      
 0.699
ugt-18
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.691
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.