STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C54F6.5Uncharacterized protein. (56 aa)    
Predicted Functional Partners:
F41C3.1
Uncharacterized protein.
      
 0.851
C40H1.3
Uncharacterized protein C40H1.3.
      
 0.759
C23G10.11
Uncharacterized protein.
   
  
 0.705
R05D7.2
SPK domain-containing protein.
      
 0.695
icmt-1
Protein-S-isoprenylcysteine O-methyltransferase.
   
  
 0.692
swan-1
WD_REPEATS_REGION domain-containing protein.
      
 0.660
cyp-34A4
Uncharacterized protein; Belongs to the cytochrome P450 family.
      
 0.660
vhl-1
Von Hippel-Lindau tumor suppressor homolog; Involved in the response to variation in environmental oxygen levels by targeting the hypoxia-inducible transcription factor hif-1 for proteasomal degradation when oxygen levels are normal (around 20%). By regulating hif-1 expression, plays a role in iron homeostasis, aging, heat acclimation and progeny size. Mediates resistance to enteropathogenic E.coli. Mediates susceptibility to B.thuringiensis pore-forming toxins. Not involved in P.aeruginosa susceptibility. Belongs to the VHL family.
      
 0.608
Y65B4BR.1
Lipase_GDSL domain-containing protein.
   
  
 0.591
kreg-1
Protein kreg-1; Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner.
   
  
 0.558
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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