STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C54G6.2C-CAP/cofactor C-like domain-containing protein. (463 aa)    
Predicted Functional Partners:
C54G6.3
Uncharacterized protein.
 
 
  
 0.838
swip-10
Lactamase_B domain-containing protein.
      
 0.809
gei-13
Gex-3-interacting protein 13.
      
 0.808
pes-10
Patterned expression site protein 10.
      
 0.611
psf-1
Probable DNA replication complex GINS protein PSF1; The GINS complex plays an essential role in the initiation of DNA replication.
      
 0.603
bckd-1B
Transket_pyr domain-containing protein.
      
 0.581
dnj-24
J domain-containing protein.
   
  
 0.553
tlk-1
Serine/threonine-protein kinase tousled-like 1; Essential for appropriate transcription during embryonic development. May act during transcription elongation to activate the RNA polymerase II large subunit (ama-1) by phosphorylating the Ser-2 residues of the C-terminal domain 7-residue repeats. Does not phosphorylate histone H3.
      
 0.547
nhr-25
Nuclear hormone receptor family member nhr-25; Orphan nuclear receptor required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop.
      
 0.532
Y48A5A.1
Protein SHQ1 homolog; Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs).
   
    0.531
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]