STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sym-3C2 NT-type domain-containing protein. (305 aa)    
Predicted Functional Partners:
sym-4
SYM-4.
   
  
 0.928
emo-1
Protein transport protein Sec61 subunit gamma; Required for oocyte development and ovulation. Required for the translocation of secretory and transmembrane proteins into the endoplasmic reticulum in vitro ; Belongs to the SecE/SEC61-gamma family.
   
 
 0.821
sym-2
RNA-binding protein sym-2; mRNA splicing factor that regulates alternative splicing of many genes in embryo. Probably plays a role in the formation of embryo- specific isoforms; Belongs to the ESRP family.
      
 0.810
mec-8
Mec-8 protein.
      
 0.758
pifk-1
PhosphoInositide Four Kinase (PI-4 Kinase); Belongs to the PI3/PI4-kinase family.
   
 0.741
sym-1
SYM-1 protein.
      
 0.740
ehbp-1
EH (Eps-15-homology) domain Binding Protein family.
      
 0.724
ags-3
Activator of G protein Signalling.
    
 
 0.685
Y75B8A.24
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.616
rpl-9
60S ribosomal protein L9; Belongs to the universal ribosomal protein uL6 family.
  
  
 0.583
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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