STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sft-4Surfeit locus protein 4 homolog; Belongs to the SURF4 family. (277 aa)    
Predicted Functional Partners:
F57B10.5
GOLD domain-containing protein.
   
 0.890
ile-1
L-type lectin-like domain-containing protein.
   
 
 0.886
F55A11.1
Uncharacterized protein.
   
  
 0.873
C29E4.14
Uncharacterized protein.
   
  
 0.869
T04F3.4
Uncharacterized protein.
   
  
 0.869
gos-28
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. Cooperates with ykt-6 for proper expression of Golgi-resident proteins. Required along with ykt-6 for normal embryonic development, seam cell division or differentiation, and ray formation.
    
 
 0.861
F54C9.7
Uncharacterized protein.
      
 0.850
sel-9
Suppressor/enhancer of lin-12 protein 9; May have a role in the negative regulation of lin-12 and glp- 1 transport to the cell surface. May also have a role in a quality control mechanism for endoplasmic reticulum-Golgi transport; the budding of coatomer-coated and other species of coated vesicles, could bind cargo molecules to collect them into budding vesicles. Involved in regulating the expression of proteasomal subunits such as rpt-3 in order to confer resistance to proteasomal dysfunction. Belongs to the EMP24/GP25L family.
   
 0.843
tag-123
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
   
  
 0.797
pes-9
M20_dimer domain-containing protein.
  
  
 0.783
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.