STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
perm-5PERMeable eggshell. (518 aa)    
Predicted Functional Partners:
C31H1.8
Uncharacterized protein.
   
  
 0.919
Y54G2A.73
Uncharacterized protein.
      
 0.896
D2096.12
Uncharacterized protein.
   
  
 0.893
F56D5.2
Uncharacterized protein.
      
 0.893
T22B11.1
Uncharacterized protein.
      
 0.891
F21D5.1
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
   
  
 0.775
trcs-1
TRansport of membrane to Cell Surface.
   
  
 0.771
dgtr-1
DGAT (Acyl-CoA:DiacylGlycerol AcylTransferase) Related.
   
  
 0.756
R148.7
Uncharacterized protein.
      
 0.740
ify-1
Securin-like protein; Acts as a chaperone and as an inhibitor for separase sep-1. Plays an essential role in maintaining chromosome cohesion prior to meiotic and mitotic anaphase, in cytokinesis and in organizing the spindle and the centrosome. Ubiquitination-dependent degradation at the onset of anaphase is likely to activate sep-1 resulting in the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. Also required for cortical granule exocytosis.
   
  
 0.712
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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