STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icd-1Transcription factor BTF3 homolog; May act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II. (161 aa)    
Predicted Functional Partners:
icd-2
Nascent polypeptide-associated complex subunit alpha; May promote appropriate targeting of ribosome-nascent polypeptide complexes.
   
 0.999
rpl-31
60S ribosomal protein L31.
   
 
 0.990
npp-11
Nuclear Pore complex Protein.
   
   0.988
rpl-25.2
60S ribosomal protein L23a 2; This protein binds to a specific region on the 26S rRNA.
   
 
 0.972
rpl-6
60S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family.
   
 
 0.972
rpl-35
60S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family.
   
   0.969
rpl-10
60S ribosomal protein L10.
   
 
 0.965
rpl-21
60S ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family.
   
   0.964
rps-19
40S ribosomal protein S19; Belongs to the eukaryotic ribosomal protein eS19 family.
   
   0.963
rpl-4
60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
   
 
 0.962
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.