STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C56E10.3Uncharacterized protein. (637 aa)    
Predicted Functional Partners:
btf-1
BTAF (TBP-associated factor) homolog.
   
 
 0.560
Y43F8B.13
Uncharacterized protein.
   
 
 0.535
ZK973.11
Thioredoxin domain-containing protein.
   
 
 0.520
T20F5.6
RING-type domain-containing protein.
    
 
 0.515
sri-43
Serpentine Receptor, class I.
   
 
 0.500
pafo-1
RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification.
    
 
 0.490
spin-1
MFS domain-containing protein.
    
 
 0.488
fbxa-24
FTH domain-containing protein.
   
  
 0.484
ari-2
Potential E3 ubiquitin-protein ligase ariadne-2; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBC-2/UBE2L3, and then transfers it to substrates. Belongs to the RBR family. Ariadne subfamily.
   
  
 0.482
str-116
Seven TM Receptor.
    
 
 0.480
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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