STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpra-1Transmembrane protein adipocyte-associated 1 homolog; Belongs to the UPF0359 family. (458 aa)    
Predicted Functional Partners:
F52E4.5
Uncharacterized protein.
   
  
 0.885
F52D10.2
PID domain-containing protein.
      
 0.810
trpa-1
Transient receptor potential cation channel subfamily A member 1 homolog; Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors.
      
 0.794
delm-1
DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.698
inx-20
Innexin; Structural component of the gap junctions. Belongs to the pannexin family.
      
 0.693
delm-2
DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.692
inx-11
Innexin-11; Structural component of the gap junctions. Belongs to the pannexin family.
      
 0.661
acd-1
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.585
pax-1
Paired domain-containing protein.
      
 0.550
tftc-1
Transcription Factor ThreeC subunit (GTF3C homolog).
   
  
 0.478
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.