STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prp-38Yeast PRP (Splicing factor) related. (320 aa)    
Predicted Functional Partners:
mfap-1
Microfibrillar-associated protein 1; Involved in pre-mRNA splicing.
   
 
 0.999
snu-23
Putative zinc finger matrin-type protein snu-23.
   
 
 0.974
prp-8
Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
   
 
 0.946
plrg-1
WD_REPEATS_REGION domain-containing protein.
 
 
   0.927
ubl-5
Ubiquitin-like protein 5.
   
 
 0.914
Y108G3AL.2
Uncharacterized protein.
   
 
  0.907
T13H5.4
Matrin-type domain-containing protein.
   
 
 0.894
cwc-15
Spliceosome-associated protein CWC15 homolog; Component of a spliceosomal complex that is required for activating pre-mRNA splicing.
   
 
 0.887
tcer-1
WW domain-containing protein.
   
 
 0.885
ZK1127.6
Uncharacterized protein.
   
 
 0.884
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.