STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rab-39RAB family. (229 aa)    
Predicted Functional Partners:
smcr-8
Guanine nucleotide exchange protein smcr-8; Part of a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy; Belongs to the SMCR8 family.
    
 0.938
rab-8
RAB family.
  
0.928
alfa-1
ALS/FTD Associated gene homolog.
   
  0.912
gdi-1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.794
rep-1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
    
 0.780
M57.2
Uncharacterized protein.
    
 0.775
rab-7
RAB family.
  
0.740
arl-3
ADP-ribosylation factor-like protein 3; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
    
 
 0.684
rab-33
Ras-related protein Rab-33.
  
0.616
4R79.2
Uncharacterized protein.
  
0.608
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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