STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdfy-2WD repeat and FYVE domain-containing protein 2; Plays a role in coelomocyte endocytosis. (415 aa)    
Predicted Functional Partners:
aps-1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
 
 
    0.878
wdfy-3
WD40 and FYVE domain protein.
   
  
 0.859
rskd-1
PX domain-containing protein.
   
  
 0.773
F13E9.1
PX domain-containing protein.
   
  
 0.748
F22G12.4
Uncharacterized protein.
    
 
 0.728
tag-77
Uncharacterized protein.
   
 
 0.713
rabn-5
FYVE-type domain-containing protein.
   
  
 0.708
rabs-5
FYVE-type domain-containing protein.
   
  
 0.704
pld-1
Phospholipase.
     
 0.701
snx-13
Sorting NeXin.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.