node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D2023.6 | F53F4.10 | D2023.6.1 | F53F4.10.1 | ABC1 domain-containing protein. | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.468 |
D2023.6 | Y32H12A.7 | D2023.6.1 | Y32H12A.7.1 | ABC1 domain-containing protein. | ABC1 domain-containing protein. | 0.985 |
D2023.6 | coq-3 | D2023.6.1 | Y57G11C.11a.2 | ABC1 domain-containing protein. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.759 |
D2023.6 | coq-4 | D2023.6.1 | T03F1.2.1 | ABC1 domain-containing protein. | Ubiquinone biosynthesis protein coq-4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.568 |
D2023.6 | coq-5 | D2023.6.1 | ZK652.9.1 | ABC1 domain-containing protein. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.580 |
D2023.6 | coq-6 | D2023.6.1 | K07B1.2.1 | ABC1 domain-containing protein. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6; Belongs to the UbiH/COQ6 family. | 0.639 |
D2023.6 | coq-8 | D2023.6.1 | C35D10.4.1 | ABC1 domain-containing protein. | Atypical kinase coq-8, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. | 0.712 |
D2023.6 | fard-1 | D2023.6.1 | Y71H10A.2.1 | ABC1 domain-containing protein. | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. | 0.491 |
D2023.6 | nuo-2 | D2023.6.1 | T10E9.7.1 | ABC1 domain-containing protein. | Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. | 0.472 |
D2023.6 | ubc-9 | D2023.6.1 | F29B9.6.2 | ABC1 domain-containing protein. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.462 |
F53F4.10 | D2023.6 | F53F4.10.1 | D2023.6.1 | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | ABC1 domain-containing protein. | 0.468 |
F53F4.10 | Y32H12A.7 | F53F4.10.1 | Y32H12A.7.1 | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | ABC1 domain-containing protein. | 0.474 |
F53F4.10 | coq-8 | F53F4.10.1 | C35D10.4.1 | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | Atypical kinase coq-8, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. | 0.468 |
F53F4.10 | nuo-2 | F53F4.10.1 | T10E9.7.1 | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. | 0.999 |
Y32H12A.7 | D2023.6 | Y32H12A.7.1 | D2023.6.1 | ABC1 domain-containing protein. | ABC1 domain-containing protein. | 0.985 |
Y32H12A.7 | F53F4.10 | Y32H12A.7.1 | F53F4.10.1 | ABC1 domain-containing protein. | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.474 |
Y32H12A.7 | coq-3 | Y32H12A.7.1 | Y57G11C.11a.2 | ABC1 domain-containing protein. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.776 |
Y32H12A.7 | coq-5 | Y32H12A.7.1 | ZK652.9.1 | ABC1 domain-containing protein. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.458 |
Y32H12A.7 | coq-8 | Y32H12A.7.1 | C35D10.4.1 | ABC1 domain-containing protein. | Atypical kinase coq-8, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. | 0.951 |
Y32H12A.7 | fard-1 | Y32H12A.7.1 | Y71H10A.2.1 | ABC1 domain-containing protein. | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. | 0.504 |