STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col-114Col_cuticle_N domain-containing protein. (321 aa)    
Predicted Functional Partners:
grl-20
Ground-like domain-containing protein.
   
  
 0.871
him-18
High Incidence of Males (Increased X chromosome loss).
    
 
 0.707
vit-4
Vitellogenin-4; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
      
 0.691
vit-3
Vitellogenin-3; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
      
 0.666
vit-1
Vitellogenin-1; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
      
 0.588
eea-1
FYVE-type domain-containing protein.
    
 
 0.509
col-118
Col_cuticle_N domain-containing protein.
  
    0.509
col-187
COLlagen.
  
     0.503
col-35
Col_cuticle_N domain-containing protein.
  
  
0.493
col-164
Col_cuticle_N domain-containing protein.
   
  
0.487
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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