STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
marc-2RING-CH-type domain-containing protein. (206 aa)    
Predicted Functional Partners:
fis-1
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
   
    0.521
marc-1
RING-CH-type domain-containing protein.
  
    0.477
ntl-2
NOT2_3_5 domain-containing protein.
    
 
 0.456
tag-153
NOT2_3_5 domain-containing protein.
    
 
 0.456
C27B7.6
Putative serine/threonine-protein phosphatase C27B7.6.
   
    0.443
ubc-14
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.425
C32D5.4
Uncharacterized protein C32D5.4.
   
    0.412
C54D10.4
Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family.
   
    0.408
ubxn-5
UBX domain-containing protein 5; Probably acts as an adapter for ATPase cdc-48.1 and/or cdc- 48.2, conferring substrate specificity. Unlike other UBX domain- containing protein does not bind 'Lys-48'-polyubiquitinated chain.
   
 
 0.408
Y73F8A.12
Uncharacterized protein.
   
    0.405
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.