STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mctp-1Multiple C2 and Transmembrane region Protein family homolog. (822 aa)    
Predicted Functional Partners:
esyt-2
C2 domain-containing protein.
      
 0.832
snx-14
PXA domain-containing protein.
   
  
 0.801
fer-1
Sperm vesicle fusion protein fer-1; Required for the fusion of the membranous organelles (MOs) with the plasma membrane, a process essential in spermiogenesis.
   
  
 0.749
tbcb-1
Tubulin-specific chaperone B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer.
      
 0.579
atln-2
GB1/RHD3-type G domain-containing protein.
   
  
 0.562
atln-1
GB1/RHD3-type G domain-containing protein.
      
 0.562
rab-18
Ras-related protein Rab-18; Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes (By similarity). Plays a role in the shedding of pathogen spores from intestinal cells.
      
 0.522
F31C3.3
Fmp27_GFWDK domain-containing protein.
      
 0.517
mce-1
Mitochondrial methylmalonyl-CoA epimerase.
   
  
 0.479
ZK524.4
Protein kinase domain-containing protein.
      
 0.461
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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