STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acr-11AcetylCholine Receptor. (461 aa)    
Predicted Functional Partners:
lgc-54
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
  
 0.644
lgc-44
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
   
 0.642
lgc-47
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
   
 0.632
lgc-45
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
   
 0.630
lgc-25
Neur_chan_LBD domain-containing protein.
  
 
0.578
lgc-26
Neur_chan_LBD domain-containing protein.
  
 
0.576
acr-25
AcetylCholine Receptor.
  
0.531
acc-4
Acetylcholine-gated ion channel acc-4; Probable acetylcholine-gated chloride channel subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. May function with lgc-46 to regulate synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons.
  
  
 0.529
acr-19
AcetylCholine Receptor.
  
  
0.481
acr-15
AcetylCholine Receptor.
  
  
0.473
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.