node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C27B7.2 | DH11.5 | C27B7.2.1 | DH11.5d.1 | Uncharacterized protein. | C2 domain-containing protein. | 0.741 |
DH11.5 | C27B7.2 | DH11.5d.1 | C27B7.2.1 | C2 domain-containing protein. | Uncharacterized protein. | 0.741 |
DH11.5 | T05H10.1 | DH11.5d.1 | T05H10.1.1 | C2 domain-containing protein. | USP domain-containing protein; Belongs to the peptidase C19 family. | 0.808 |
DH11.5 | cpx-1 | DH11.5d.1 | Y73E7A.4.1 | C2 domain-containing protein. | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | 0.672 |
DH11.5 | gar-2 | DH11.5d.1 | F47D12.1c.1 | C2 domain-containing protein. | Muscarinic acetylcholine receptor gar-2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Regulates the activity of ventral cord motor neurons. Couples to the G(o) alpha G-protein subunit goa-1 to negatively regulate cholinergic receptor activity in the presence of high levels of the neurotransmitter acetylcholine in ventral cord motor neurons. As acetylcholin [...] | 0.661 |
DH11.5 | rab-3 | DH11.5d.1 | C18A3.6a.1 | C2 domain-containing protein. | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | 0.680 |
DH11.5 | ric-4 | DH11.5d.1 | Y22F5A.3b.1 | C2 domain-containing protein. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.711 |
DH11.5 | snt-4 | DH11.5d.1 | T23H2.2.1 | C2 domain-containing protein. | SyNapTotagmin. | 0.760 |
DH11.5 | unc-13 | DH11.5d.1 | ZK524.2d.1 | C2 domain-containing protein. | Phorbol ester/diacylglycerol-binding protein unc-13; May form part of a signal transduction pathway, transducing the signal from diacylglycerol to effector functions. One such function could be the release of neurotransmitter from neurons. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt. | 0.701 |
DH11.5 | unc-25 | DH11.5d.1 | Y37D8A.23a.1 | C2 domain-containing protein. | Glutamic acid decarboxylase. | 0.661 |
DH11.5 | unc-41 | DH11.5d.1 | C27H6.1a.1 | C2 domain-containing protein. | Putative stoned B-like protein; Potential adapter protein, which may be involved in endocytic vesicle recycling of synaptic vesicles; Belongs to the Stoned B family. | 0.656 |
T05H10.1 | DH11.5 | T05H10.1.1 | DH11.5d.1 | USP domain-containing protein; Belongs to the peptidase C19 family. | C2 domain-containing protein. | 0.808 |
cpx-1 | DH11.5 | Y73E7A.4.1 | DH11.5d.1 | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | C2 domain-containing protein. | 0.672 |
cpx-1 | rab-3 | Y73E7A.4.1 | C18A3.6a.1 | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | 0.717 |
cpx-1 | ric-4 | Y73E7A.4.1 | Y22F5A.3b.1 | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.839 |
cpx-1 | snt-4 | Y73E7A.4.1 | T23H2.2.1 | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | SyNapTotagmin. | 0.409 |
cpx-1 | unc-13 | Y73E7A.4.1 | ZK524.2d.1 | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | Phorbol ester/diacylglycerol-binding protein unc-13; May form part of a signal transduction pathway, transducing the signal from diacylglycerol to effector functions. One such function could be the release of neurotransmitter from neurons. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt. | 0.800 |
cpx-1 | unc-25 | Y73E7A.4.1 | Y37D8A.23a.1 | Putative complexin-1; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family. | Glutamic acid decarboxylase. | 0.589 |
gar-2 | DH11.5 | F47D12.1c.1 | DH11.5d.1 | Muscarinic acetylcholine receptor gar-2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Regulates the activity of ventral cord motor neurons. Couples to the G(o) alpha G-protein subunit goa-1 to negatively regulate cholinergic receptor activity in the presence of high levels of the neurotransmitter acetylcholine in ventral cord motor neurons. As acetylcholin [...] | C2 domain-containing protein. | 0.661 |
gar-2 | ric-4 | F47D12.1c.1 | Y22F5A.3b.1 | Muscarinic acetylcholine receptor gar-2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Regulates the activity of ventral cord motor neurons. Couples to the G(o) alpha G-protein subunit goa-1 to negatively regulate cholinergic receptor activity in the presence of high levels of the neurotransmitter acetylcholine in ventral cord motor neurons. As acetylcholin [...] | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.475 |