STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hlh-16BHLH domain-containing protein. (146 aa)    
Predicted Functional Partners:
pqn-26
Glutaredoxin domain-containing protein.
      
 0.851
lin-32
Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis.
   
 
 0.820
hlh-19
BHLH domain-containing protein.
   
 
 0.718
wht-6
ABC transporter domain-containing protein.
   
  
 0.702
Y37A1B.17
Uncharacterized protein.
   
  
 0.697
wht-8
ABC transporter domain-containing protein.
   
  
 0.667
wht-2
ABC transporter domain-containing protein.
   
  
 0.665
wht-3
ABC transporter ATP-binding protein/permease wht-3; Required for efficient RNA interference (RNAi) of pop-1 indicating a role in the germline development. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
   
  
 0.664
ccch-2
CCCH-type zinc finger putative transcription factor.
      
 0.664
grl-12
Ground-like domain-containing protein.
   
  
 0.662
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.