STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqn-26Glutaredoxin domain-containing protein. (664 aa)    
Predicted Functional Partners:
hlh-16
BHLH domain-containing protein.
      
 0.851
rnr-1
Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.711
trt-1
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
      
 0.697
msra-1
PMSR domain-containing protein.
  
 
 0.602
gsr-1
Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. Involved in resistance to oxidative stress and starvation. Together with thioredoxin reductase txtr- 1, required for the reduction of disulfide groups in the cuticle during molting.
  
 0.560
pqn-13
Prion-like-(Q/N-rich)-domain-bearing protein.
   
    0.547
Y39B6A.3
Fe-S_biosyn domain-containing protein.
  
  
 0.544
M02G9.1
Uncharacterized protein.
   
    0.541
K04H4.2
Uncharacterized protein K04H4.2.
   
    0.531
trxr-1
Thioredoxin reductase 1; Together with glutathione reductase gsr-1, required for the reduction of disulfide groups in the cuticle during molting.
  
 0.507
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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