node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0310.2 | D2045.7 | B0310.2a.1 | D2045.7.1 | Putative zinc finger protein B0310.2. | Protein kinase domain-containing protein. | 0.553 |
B0310.2 | isw-1 | B0310.2a.1 | F37A4.8.1 | Putative zinc finger protein B0310.2. | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | 0.623 |
B0310.2 | lin-66 | B0310.2a.1 | B0513.1a.1 | Putative zinc finger protein B0310.2. | Uncharacterized protein. | 0.641 |
B0310.2 | madd-3 | B0310.2a.1 | E02H4.3e.1 | Putative zinc finger protein B0310.2. | Probable dual specificity protein kinase madd-3; [Isoform a]: Probable dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Negatively regulates p38 MAPK signaling to allow for the plasma membrane of body wall muscle cells to form projections, also called muscle arms, that extend and connect the body wall muscles to target motor neurons. Negative regulation of p38 MAPK signaling may in turn modulate the trafficking of the muscle specific receptor eva-1 to the lysosome, to ensure proper display of the eva-1 receptor on the plasma membrane of muscle [...] | 0.587 |
B0310.2 | mask-1 | B0310.2a.1 | R11A8.7f.1 | Putative zinc finger protein B0310.2. | Ankyrin repeat and KH domain-containing protein mask-1; Belongs to the mask family. | 0.556 |
B0310.2 | mes-3 | B0310.2a.1 | F54C1.3a.1 | Putative zinc finger protein B0310.2. | Polycomb protein mes-3; Component of a Polycomb group (PcG) complex. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes- 6 complex may participate in the global inactivation of the X chromosomes in germline cells. The complex may act via methylation of histone H3 'Lys-27', rendering chromatin heritably changed in its expressibility. This complex is [...] | 0.588 |
B0310.2 | rha-1 | B0310.2a.1 | T07D4.3.1 | Putative zinc finger protein B0310.2. | ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Binds to DNA, RNA and small interfering siRNA. Plays a role in DNA replicat [...] | 0.502 |
B0310.2 | ten-1 | B0310.2a.1 | R13F6.4e.1 | Putative zinc finger protein B0310.2. | Teneurin-1; Plays a role in the gonadal basement membrane maintenance and/or adhesion early in development. Contributes to the guidance of pharyngeal neurons. | 0.604 |
D2045.7 | B0310.2 | D2045.7.1 | B0310.2a.1 | Protein kinase domain-containing protein. | Putative zinc finger protein B0310.2. | 0.553 |
D2045.7 | isw-1 | D2045.7.1 | F37A4.8.1 | Protein kinase domain-containing protein. | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | 0.552 |
D2045.7 | lin-66 | D2045.7.1 | B0513.1a.1 | Protein kinase domain-containing protein. | Uncharacterized protein. | 0.592 |
D2045.7 | madd-3 | D2045.7.1 | E02H4.3e.1 | Protein kinase domain-containing protein. | Probable dual specificity protein kinase madd-3; [Isoform a]: Probable dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Negatively regulates p38 MAPK signaling to allow for the plasma membrane of body wall muscle cells to form projections, also called muscle arms, that extend and connect the body wall muscles to target motor neurons. Negative regulation of p38 MAPK signaling may in turn modulate the trafficking of the muscle specific receptor eva-1 to the lysosome, to ensure proper display of the eva-1 receptor on the plasma membrane of muscle [...] | 0.571 |
D2045.7 | mask-1 | D2045.7.1 | R11A8.7f.1 | Protein kinase domain-containing protein. | Ankyrin repeat and KH domain-containing protein mask-1; Belongs to the mask family. | 0.564 |
D2045.7 | mes-3 | D2045.7.1 | F54C1.3a.1 | Protein kinase domain-containing protein. | Polycomb protein mes-3; Component of a Polycomb group (PcG) complex. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes- 6 complex may participate in the global inactivation of the X chromosomes in germline cells. The complex may act via methylation of histone H3 'Lys-27', rendering chromatin heritably changed in its expressibility. This complex is [...] | 0.556 |
D2045.7 | rha-1 | D2045.7.1 | T07D4.3.1 | Protein kinase domain-containing protein. | ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Binds to DNA, RNA and small interfering siRNA. Plays a role in DNA replicat [...] | 0.456 |
D2045.7 | ten-1 | D2045.7.1 | R13F6.4e.1 | Protein kinase domain-containing protein. | Teneurin-1; Plays a role in the gonadal basement membrane maintenance and/or adhesion early in development. Contributes to the guidance of pharyngeal neurons. | 0.611 |
ech-2 | madd-3 | F38H4.8b.1 | E02H4.3e.1 | Enoyl-CoA Hydratase. | Probable dual specificity protein kinase madd-3; [Isoform a]: Probable dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Negatively regulates p38 MAPK signaling to allow for the plasma membrane of body wall muscle cells to form projections, also called muscle arms, that extend and connect the body wall muscles to target motor neurons. Negative regulation of p38 MAPK signaling may in turn modulate the trafficking of the muscle specific receptor eva-1 to the lysosome, to ensure proper display of the eva-1 receptor on the plasma membrane of muscle [...] | 0.588 |
ech-2 | rib-1 | F38H4.8b.1 | F12F6.3a.1 | Enoyl-CoA Hydratase. | Exostosin-1 homolog; Required for the biosynthesis of heparan sulfate by positively regulating N-acetylglucosamine transferase II (GlcNAcT-II) and glucuronyl transferase II (GlcAT-II) activities of glycosyltransferase rib-2. Probably not directly involved in chondroitin sulfate biosynthesis but negatively regulates chondroitin sulfate levels. Maternally required for normal ventral epidermal enclosure and for embryo elongation during the early stages of embryonic development. In addition, involved in the elongation of the pharyngeal isthmus and in the organization of the actin cytoskele [...] | 0.610 |
isw-1 | B0310.2 | F37A4.8.1 | B0310.2a.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Putative zinc finger protein B0310.2. | 0.623 |
isw-1 | D2045.7 | F37A4.8.1 | D2045.7.1 | Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. | Protein kinase domain-containing protein. | 0.552 |