STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-174Nuclear hormone receptor family member nhr-174; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. (319 aa)    
Predicted Functional Partners:
nhr-276
Nuclear Hormone Receptor family.
   
  
 0.893
Y87G2A.2
Uncharacterized protein.
      
 0.891
C05C9.3
Uncharacterized protein.
   
   0.858
nhr-169
Nuclear hormone receptor family member nhr-169; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
  
  
0.854
dyf-5
Serine/threonine-protein kinase dyf-5; Serine/threonine-protein kinase which is required for ciliogenesis. Regulates the length and the morphology of sensory neuron cilia. In addition, plays a role in the anterograde intraflagellar transport (IFT) in the cilia by regulating the undocking of kinesin-II motor complex (composed of klp-11, klp-20 and kap-1) before reaching the distal segment and the docking of kinesin motor osm-3 onto IFT cargos; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. RCK subfamily.
   
   0.852
kin-6
Non-specific protein-tyrosine kinase.
   
   0.852
math-6
MATH (Meprin-associated Traf homology) domain containing.
   
   0.851
srw-119
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
   0.850
srr-7
Serpentine Receptor, class R.
   
   0.850
srw-133
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
   0.850
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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