STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcrg-1Parkin Co-Regulated Gene (PACRG) homolog. (294 aa)    
Predicted Functional Partners:
efhc-1
EF-Hand domain-Containing protein 1 homolog.
  
 
 0.993
C54C6.6
Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility; Belongs to the CFAP20 family.
    
 
 0.936
E04F6.6
Uncharacterized protein.
      
 0.890
gpa-11
Guanine nucleotide-binding protein alpha-11 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Mediates the transduction of food and serotonin signals, which modulates the avoidance response to the odorant octanol. Has a role in lifespan to promote longevity.
   
  
 0.740
cpn-2
Transgelin; Belongs to the calponin family.
    
 
 0.689
cpn-3
Calponin-homology (CH) domain-containing protein.
    
 
 0.689
cpn-1
Calponin-homology (CH) domain-containing protein.
    
 
 0.689
cpn-4
Calponin-homology (CH) domain-containing protein.
    
 
 0.689
mgl-2
G_PROTEIN_RECEP_F3_4 domain-containing protein.
   
 
 0.668
mgl-3
G_PROTEIN_RECEP_F3_4 domain-containing protein.
   
 
 0.668
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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