STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E04F6.4Uncharacterized protein. (635 aa)    
Predicted Functional Partners:
Y43F8B.1
Uncharacterized protein.
      
 0.697
Y92H12BR.3
Uncharacterized protein Y92H12BR.3.
      
 0.697
ZK1098.11
N-acetyltransferase domain-containing protein.
      
 0.697
R09E10.5
Uncharacterized protein R09E10.5.
      
 0.694
dph-2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. Belongs to the DPH1/DPH2 family. DPH2 subfamily.
      
 0.693
D1086.1
DUF19 domain-containing protein.
      
 0.688
C23H4.3
Carboxyl ESTerase domain containing.
   
  
 0.668
C24H12.4
Helicase C-terminal domain-containing protein.
      
 0.660
ttr-51
TransThyretin-Related family domain.
      
 0.660
gst-36
Probable glutathione S-transferase gst-36; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Sigma family.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.