STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhs-7DeHydrogenases, Short chain. (329 aa)    
Predicted Functional Partners:
dhs-6
SCP2 domain-containing protein.
  
 0.889
pks-1
PolyKetide Synthase.
  
 0.839
viro-2
WH1 domain-containing protein.
    
 
 0.765
dhs-23
DeHydrogenases, Short chain.
   
 
 0.704
nrf-6
Nose resistant to fluoxetine protein 6; Plays a role in the uptake of a range of molecules including lipids and xenobiotic compounds from the intestine to surrounding tissues. Mediates transport of lipids from intestine to the reproductive tract. Required for efficient yolk transport into oocytes. Vital for embryonic development; Belongs to the acyltransferase 3 family.
   
  
 0.670
R05H5.5
ARV1 homolog.
      
 0.664
hsp-12.2
Heat shock protein Hsp-12.2; Belongs to the small heat shock protein (HSP20) family.
      
 0.639
B0280.2
Uncharacterized protein B0280.2.
    
 
 0.628
C31C9.6
WH1 domain-containing protein.
    
 
 0.628
sid-3
Tyrosine-protein kinase sid-3; Tyrosine-protein kinase which plays a role in RNA-mediated gene silencing by mediating import of double-stranded RNA (dsRNA) into cells. Not required for import of ingested dsRNA into intestinal cells but involved in subsequent export from intestinal cells to internal tissues.
    
 
 0.609
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.