STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndx-6Putative nudix hydrolase 6; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. (260 aa)    
Predicted Functional Partners:
R151.2
Pribosyltran_N domain-containing protein.
     
 0.906
R05F9.6
Uncharacterized protein; Belongs to the phosphohexose mutase family.
     
  0.900
Y43F4B.5
Uncharacterized protein; Belongs to the phosphohexose mutase family.
     
  0.900
syx-6
Putative syntaxin 6; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family.
      
 0.838
gtl-2
Gon-Two Like (TRP subfamily).
 
    
 0.752
rsp-4
Probable splicing factor, arginine/serine-rich 4; May play a functionally redundant role in embryogenesis. Belongs to the splicing factor SR family.
 
 
    0.750
npp-16
Nuclear Pore complex Protein.
   
  
 0.748
ndx-2
Putative nudix hydrolase 2; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.
      
 0.650
C50F4.16
Nudix hydrolase domain-containing protein.
   
 
 0.646
ndx-1
Putative nudix hydrolase 1; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.
      
 0.623
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.